Immunology & Pathogenesis

Upper Division Requirements, Sample 4-yr Plans, Elective Lists

Humans inhabit an environment teeming with microbes and their toxins. The omnipresent threat of infection and the emergence of new infectious diseases has catapulted immunology to the forefront of modern biomedical science. Immunology is the study of the cellular and biochemical mechanisms which protect us from these threats. Infectious agents such as human immunodeficiency virus which causes AIDS and immune-based diseases such as asthma have increased the public awareness about the importance of immunology in examining the causes and treatments of these diseases. Immunology is unique amongst the natural sciences in that it covers and integrates aspects of modern biological science including cell and developmental biology, biochemistry, genetics, and molecular biology.

Using approaches from many disciplines and techniques as diverse as recombinant DNA, flow cytometry, physical chemistry, mouse transgenesis, and targeted mutation in mice, immunologists have made major advances and striking discoveries leading to an ever-growing understanding of the immune system. We continue to explore questions such as how the immune system distinguishes self from non-self, how antibodies, T cells and natural killer cells specifically recognize and distinguish millions of different foreign invaders, why some individuals are more susceptible to the development of autoimmune diseases, and how the immune system rejects transplanted organs but often fails to reject tumors. In addition, immunologists study questions of broader biological significance including how gene expression is regulated during animal development, the biochemistry and regulation of gene rearrangement, the mechanism and function of immune surveillance, and the control of programmed cell death.

These recent advances in basic knowledge have in turn led to potential treatments for autoimmune diseases and cancers, new approaches to the design of effective vaccines, strategies to combat AIDS, and treatments to prevent tissue transplant rejection. Students with an emphasis in Immunology will be exposed not only to the unique aspects of the immune system but also to a broad array of disciplines across the full spectrum of modern biomedical sciences.

Upper Division Requirements

Immunology and Pathogenesis
Track 1: Immunology and Pathogenesis Track 2: Infectious Disease
MCB C100A: Biophysical Chemistry (Fa, Sp; 4 un) MCB 102: Biochemistry and Molecular Biology (Fa, Sp, Su; 4 un)
MCB 110: Molecular Biology: Macromolecular Synthesis & Cellular Function (Fa, Sp; 4 un) MCB 104:  Genetics, Genomics, & Cell Biology (Fa, Sp; 4 un) OR MCB 140: General Genetics (Fa, Sp; 4 un)
MCB 104:  Genetics, Genomics, & Cell Biology (Fa, Sp; 4 un) OR MCB 140: General Genetics (Fa, Sp; 4 un) MCB 150: Molecular Immunology (Fa, Sp; 4 un)
MCB 150: Molecular Immunology (Fa, Sp; 4 un) MCB 150L: Immunology Lab (Fa, Sp; 4 un)
MCB 150L: Immunology Lab (Fa, Sp; 4 un) IMM Elective A (see list below)
IMM Elective C (see list below) IMM Elective B (see list below)

 

Petitioning to Substitute MCB 150L with Research Units

Students may petition to substitute the lab course with equivalent knowledge and units obtained through independent research experience (such as 199 or H196 research), as determined by the Head Faculty Advisor of their major emphasis. Careful consideration and discussion with your faculty advisor is important when making the decision whether to use independent research to substitute the lab, as MCB labs expose students to many biological approaches not always encountered during these research projects. For more information on the approval process see Petition to Substitute MCB Lab Course.

Sample 4-yr Plans

These are just examples, for more sample schedules including spring start and transfer see guide.berkeley.edu or meet with an advisor to explore your options.It is recommended by MCB advisors and faculty to take the upper division lab as early as you can if you are interested in research and/or honors research. 

Track 1: Immunology & Pathogenesis   Track 2: Infectious Disease
Year 1   Year 1
Fall Un Spring Un   Fall Un Spring Un
Math 10A 4 Math 10B 4   Math 10A 4 Math 10B 4
Chem 1A/1AL 4 Chem 3A/3AL 5   Chem 1A/1AL 4 Chem 3A/3AL 5
Year 2   Year 2
Fall Un Spring Un   Fall Un Spring Un
Chem 3B/3BL 5 Biology 1A/1AL 5   Chem 3B/3BL 5 Biology 1A/1AL 5
Physics 8A 4 Physics 8B 4   Physics 8A 4 Physics 8B 4
Year 3   Year 3
Fall Un Spring Un   Fall Un Spring Un
MCB C100A 4 MCB 150 4   MCB 102 4 MCB 104 or 140 4
Biology 1B 4 MCB 150L 5   Biology 1B 4 Elective A 3-4
Year 4   Year 4
Fall Un Spring Un   Fall Un Spring Un
MCB 110 4 Elective C 3-4   MCB 150 4 IMM Elective B 3-4
MCB 104 or 140 4       MCB 150L 4    

 

Approved Electives Lists

IMM Elective List C

IMM Elective Lists A/B

Molecular & Cell Biology

  • 100B Biochemistry: Pathways, Mechanisms, and Regulation (Sp; 4 units)
  • C103 Bacterial Pathogenesis (Sp; 3 units) - not offered Sp15
  • C112 General Microbiology (F, Su; 4 units)
  • C114 Intro to Comparative Virology (Sp; 4 units)
  • 130 Cell & Systems Biology (Sp; 4 units)
  • 132 Biology of Human Cancer (F; 4 units)
  • C134 Chromosome Biology/Cytogenetics (S; 3 units)
  • 135A Molecular Endocrinology (F; 3 units)
  • 141 Developmental Biology (Sp; 4 units)
  • 149 The Human Genome (Sp; 3 units)
  • 250 Advanced Immunology (Sp; 4 units)

Bioengineering

  • 131 Introduction to Computational Molecular and Cell Biology (Fa; 4 units)

Elective List A
Molecular & Cell Biology

  • C103 Bacterial Pathogenesis (Sp, 3 units)
  • C112 General Microbiology (F, Su; 4 units)
  • C114 Intro to Comparative Virology (Sp, 4 units)

Elective List B
Molecular & Cell Biology

  • 130 Cell & Systems Biology (Sp; 4 units)
  • 132 Biology of Cancer (F; 4 units)
  • C134 Chromosome Biology/Cytogenetics (Sp; 3 units)
  • 135A Molecular Endocrinology (F; 3 units)
  • 136 Physiology (F; 4 units)
  • 141 Developmental Biology (Sp; 4 units)
  • 143 Evolution of Genomes, Cells & Development (F; 3 units)
  • 149 The Human Genome (Sp; 3 units)
  • 160 Cellular and Molecular Neurobiology (F; 4 units)
  • 161 Circuit, Systems and Behavorial Neuroscience (Sp; 4 units) *MCB 160 is a prerequisite*
  • 250 Advanced Immunology (Sp; 4 units)
     

Approved Courses but Not Regularly offered

  • MCB C145 Genomics
  • MCB C146 Topics in Computational Biology & Genomics